Make a difference in global healthcare!

At Immunetrics, you have the ability to carve out your own career path: to learn about areas that interest you, to join a specialized team, and to create challenging, innovative, mechanistic modeling solutions. Our employees come from many different specialties, including biology, computer science, engineering, and mathematics.

Open Positions

Immunetrics is looking for talented people to join our multidisciplinary team. If you believe that you would be a valuable addition to our team, please send a resume and cover letter to careers@immunetrics.com.

We believe in what we do and its potential benefit in improving clinical outcomes. We believe that respect and integrity in dealing with each other and our customers is the secret to being successful as a team and as a business. We believe in rewarding hard work and initiative and in helping our employees to realize their potential.
Immunetrics is an equal opportunity employer.

Responsibilities Include:

  • Developing, maintaining, and extending simulation infrastructure code for proprietary biological modeling software platform
  • Assist scientific programmers, data scientists, and mathematical modelers in designing and implementing software solutions for scientific computation problems
  • Working with scientific user-base and architects to solicit new features and improve users’ workflow
  • Analyzing algorithm performance and optimizing code for computational efficiency
  • Responsible for all aspects of software process: design, prototyping, debugging, testing, etc.
  • Helping end-users troubleshoot problems
  • Contributing to documentation
  • Periodically assisting with small-scale system administration / IT tasks


  • Minimum of BS in Computer Science.
  • Strong background in algorithms, data structures, and software engineering principles is essential.
  • Commitment to writing elegant, reliable, robust software is essential.
  • Proficient programming skills in at least one of the following: Python or C++. Proficiency in Java is desirable but not required.
  • Solid object-oriented design skills, testing and debugging skills are required.
  • Strong background and interest in mathematics is desirable.
  • Eagerness to work in a team-oriented, small company environment

All candidates must have authorization to work in the U.S. 

To apply, please send resume and cover letter to careers@immunetrics.com.
Immunetrics is an equal opportunity employer.

Responsibilities Include:

  • Develop expert reviews of varying subject matter (50%)
    • Develop an understanding of cellular and molecular biology, immunology, physiology, and clinical trial-related concepts relevant to a wide range of Immunetrics’ projects through detailed scientific literature searches. This research will vary in scope from fine molecular and experimental details to general concepts in healthy and disease-state physiology.
    • Provide biological expertise that represents the foundation for the development of Immunetrics’ mathematical models in the form of influence diagrams, written reports, and specification sheets.
  • Clinical data analysis (25%)
    • Organize and analyze clinical trial data and databases from published and proprietary sources.
    • Critically collect, analyze, and interpret published data into a context which can be understood and utilized by Immunetrics’ team of mathematical modelers.
    • Maintain documentation of literature supporting model design decisions.
  • Project management (10%)
    • Work with the QSP Platform Manager to provide leadership for assigned projects, including statements of work, time estimates, and project progress tracking.
    • Closely work with mathematical modelers on the development, documentation, and maintenance of new and existing quantitative models of various disease states.
    • Organize and prepare background information, data, and results for internal and external communications and presentations.
  • Science communication (10%)
    • Communicate scientific information and model design rational to colleagues and clients who have expertise in a variety of disciplines.
    • Prepare marketing material for external communication and business development activities.
  • Other (5%)
    • Participate in a variety of internal and external projects as assigned.


  • Applicants should have a PhD in a biology-related field with a strong background in molecular/cellular biology.
  • The desired candidate will have knowledge of cellular signaling pathways and how they relate to immune response and regulation.  
  • Demonstrated skills in scientific writing and communication.
  • The ability to explain biological concepts to non-biologists.
  • Exceptional organizational skills.
  • The candidate must demonstrate great attention to detail while maintaining a clear vision of overall project goals to ensure project success. 
  • The candidate must be capable of working effectively both independently and in a team setting.
  • The candidate must be able to be effective when working on multiple concurrent projects, which requires the ability to prioritize and thoroughly plan workflow processes.

Preference Given for:

  • A background in immunology or immuno-oncology are strongly preferred.
  • Knowledge of the pathology of autoimmune disease or cancer is also strongly preferred. 
  • A strong knowledge and understanding of human physiology are preferred.
  • Clinical research experience is a plus.
  • Pittsburgh, PA area candidates are preferred.

All candidates must have authorization to work in the U.S.

To apply, please send resume and cover letter to: careers@immunetrics.com.
Immunetrics is an equal opportunity employer.

©2022 Immunetrics Inc.

Immunetrics provides Quantitative Systems Pharmacology (QSP) modeling services to pharmaceutical companies to provide critical insight so that they can make informed decisions from the selection of candidate drugs to designing clinical trials.

Immunetrics’ suite of model development and virtual population generation tools coupled with our extensive library of physiological and clinical data allow us to build models which can accurately reproduce and predict the effect of therapeutic compounds from the intracellular scale all the way to the outcomes of phase III clinical trials.

Immunetrics is seeking highly-motivated professionals who would like to affect positive change in the way potential therapeutics are selected and evaluated.

A QSP Mathematical Modeler working for Immunetrics will be part of a multidisciplinary team of professionals who design and develop mechanistic computational models of complex biological systems to support our clients’ needs.  As a member of this team, the modeler will work with both internal and client biologists to utilize research literature to understand biological pathways and physiological processes. The modeler’s responsibilities will span the entire modeling life cycle: analysis, specification, design, implementation, parameter estimation, model training, testing, debugging, population generation, verification, validation, documentation, and maintenance. 

This position will report to the QSP Modeling Platform Manager.

Position Description:

  • Collaborate with a multidisciplinary team of both internal and external professionals to develop, test, and utilize disease specific, mechanistic models of human physiology.
  • Analyze systems of complex interactions, evaluate the data available to constrain system behavior, and then determine the appropriate level of detail or abstraction needed to best represent the system.
  • Utilize Immunetrics’ modeling platforms to build and constrain the behavior of models.
  • Perform parameter estimation using empirical data and analyze the sensitivity of model parameters.
  • Configure model execution scenarios and pipelines to emulate complex clinical trial protocols.
  • Generate diverse virtual populations which statistically replicate results from multiple clinical trials.
  • Execute and analyze model results and determine a course of action to resolve any model deficiencies.
  • Work with client professionals to design virtual experiments to better inform their decision process.
  • Maintain and extend existing QSP models.
  • Author and maintain detailed model documentation.
  • Communicate research and findings to technical and non-technical audiences inside and outside the company.
  • Participate in the contract process by estimating effort and defining feasible project scope.
  • Mentor less experienced modelers and provide platform training when needed.


  • PhD or MS in Chemical Engineering, Electrical Engineering, Mathematics, Physics or other fields related to quantitative system pharmacology.
  • Experience which demonstrates a strong emphasis on computational modeling of biologic systems.
  • Strong background in numerical computation and complex systems of equations, especially differential equations and parameter estimation.
  • Ability to understand complex biologic systems and represent those systems mathematically. A strong understanding of reaction kinetics is essential.
  • Thorough understanding of the basic principles of standard pharmacokinetic models.
    Foundational knowledge of biology and the ability to quickly learn and apply new knowledge.
  • Ability to apply knowledge of biology to develop mechanistic QSP models.
  • Prior mechanistic modeling experience or background is required.
  • A functional knowledge of statistics is necessary.
  • Strong verbal and written communication skills are necessary, especially the ability to summarize and explain the results and implications of modeling simulations to other members of the project team.
  • Ability to work effectively with others as a member of a multidisciplinary team is required.

Preference Given for:

  • Demonstrated ability to understand complex systems at a high level and make abstractions to represent the function of subsystems.
  • Prior systems modeling experience or background in one or more of the following domains: inflammation, immunology, cell signaling, oncology, or physiology.
  • Demonstrated ability to deliver concrete project tasks on schedule.
  • Relevant industry experience including but not limited to: demonstrated ability to deliver concrete project tasks on schedule, experience estimating effort required for individual project tasks, and the ability to work effectively in a multi-disciplinary team.

All candidates must have authorization to work in the U.S.

To apply, please send resume and cover letter to careers@immunetrics.com.

Immunetrics is an equal opportunity employer.

©2022 Immunetrics Inc.

Culture and Impact

Work Culture

Immunetrics employees come from many different backgrounds, including mathematics, software, and, of course, biology. We internally collaborate on all projects, gathering expertise and valuing the opinions of all employees. We are fundamentally committed to personal growth, to work-life balance, and to meeting the needs of our employees. Immunetrics is an equal opportunities employer.


Our employees are united by an altruistic goal—to apply massive computational capabilities and modeling sophistication to address many of the most pressing needs in healthcare. Our culture is enriched by a work environment emphasizing innovation and collaboration. Here’s what some of our employees had to say when we asked them to summarize why they work for Immunetrics.


Immunetrics is located in Pittsburgh, PA, USA, consistently recognized as one of the most livable cities in the United States. The regional economy is built on healthcare, technology, education, and finance. Pittsburgh has emerged as a capital of fine arts, sports, dining, parks, and river life–with an affordable cost of living.