Immunetrics’ suite of core modeling components can be used independently for experimental studies and/or combined with other components to create representative conditions and disease states.
Our core cell and physiology models were developed to accurately represent the highly interconnected nature of biology and are constantly evolving as new research is published. These models are available for licensing.
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Immunology |
Physiology |
Critical Care |
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TH1 cells TH2 cells TH17 cells TH22 cells
Monocytes Macrophages Neutrophils Eosinophils Mast cells Endothelial cells Epithelial cells Keratinocytes |
Cardiovascular system Renal system Pulmonary system Skin Joints |
Coagulation Trauma Inflammation |
Disease Specific Models
Immunetrics’ disease-specific models span acute inflammation and chronic, autoimmune conditions. Immunetrics’ disease specific models can be customized to meet specific needs and are constantly evolving to support new research outcomes. These models are available for licensing and for use in consulting projects. Disease Models Key Outputs Supported Therapeutics Rheumatoid Arthritis Psoriatic Arthritis / Psoriasis Ulcerative Colitis Serum cytokines and biomarkers Serum cell counts Swollen/tender joint counts ACR20/50/70 DAS28(3)-CRP/ESR PASI 50/75/90/100 Mayo score Response/Remission MTX 5-ASA Corticosteroids JAK inhibitors Anti-TNFs Anti-IL6s Anti-IL17s Anti-T and B cell therapies Anti-Survival therapies Anti-Migration therapies Sepsis Multi-Organ Dysfunction Trauma Mean arterial pressure (MAP) Central venous pressure (CVP) Blood oxygen saturation (O2sat) Breathing frequency Tidal volume Blood gases (PaO2, PaCO2) Creatinine Urinary output (UOP) Coagulation tests (PT, APTT) Fluid therapy Vasopressors Ventilators Diuretics Dialysis Antibiotics