We specialize in supporting client decisions in clinical trials and drug development in the field of immunology. Through our vast collection of research and model components, we can apply pre-built model components to your project, build novel models, or license our technology for your model development and prediction needs.
Immunetrics has a suite of core modeling components (individual immune cells, organ systems, and biological processes) that can be used independently for modeling analyses and/or combined with other components to support new disease states or conditions. Models are constantly evolving as new research is published, and are typically customized to meet specific client goals.
|
Immunology |
Physiology |
Critical Care |
|
TH1/2/17/22 Tregs CD8+ T cells
Monocytes/Macrophages Neutrophils Eosinophils Mast cells Endothelial cells Epithelial cells Keratinocytes |
Cardiovascular system Renal system Pulmonary system Skin Joints |
Inflammation Coagulation/Bleeding Trauma
|
- Core models can be recombined to rapidly develop and customize patient-level models of many disease states
- Interested in a disease area or cell not mentioned on our website? Contact Us
Disease Specific Models
Immunetrics’ disease models span across acute inflammation, chronic, autoimmune conditions, and immuno-oncology. These models can be customized to meet specific needs and are constantly evolving to support new research outcomes. Disease Models Key Outputs Supported Therapeutics Rheumatoid Arthritis ACR20/50/70 DAS28(3)-CRP/ESR Low disease activity Remission Serum cytokines and biomarkers Serum cell counts 5-ASA Corticosteroids JAK inhibitors Anti-TNFs Anti-IL6s Anti-IL17s Anti-T and B cell therapies Anti-Survival therapies Anti-Migration therapies Psoriatic Arthritis / Psoriasis ACR20/50/70 DAS28(3)-CRP/ESR PASI 50/75/90/100 Serum cytokines and biomarkers Serum cell counts 5-ASA Corticosteroids JAK inhibitors Anti-TNFs Anti-IL6s Anti-IL17s Anti-IL12/23 Anti-T and B cell therapies Anti-Survival therapies Anti-Migration therapies Ulcerative Colitis Response/Remission Mucosal healing Serum cytokines and biomarkers 5-ASA Corticosteroids Anti-TNFs JAK inhibitors S1P receptor antagonist Melanoma Lymphoma Leukemia Lesion size changes Serum cytokines and biomarkers Sepsis Multi-Organ Dysfunction Central venous pressure (CVP) Blood oxygen saturation (O2sat) Breathing frequency Tidal volume Blood gases (PaO2, PaCO2) Creatinine Urinary output (UOP) Coagulation proteins Vasopressors Ventilators Diuretics Dialysis Antibiotics Trauma Immune cells Coagulation proteins Blood loss Mean arterial pressure (MAP) Blood oxygen saturation (O2sat) Blood products Ventilators
Swollen/tender joint counts
MTX
Swollen/tender joint counts
MTX
Mayo score
MTX
Immuno-oncology
RECIST criteria
Proprietary
Mean arterial pressure (MAP)
Fluid therapy
Cytokines
Fluid therapies