Immunetrics’ suite of core modeling components can be used independently for experimental studies and/or combined with other components to create representative conditions and disease states.

Our core cell and physiology models were developed to accurately represent the highly interconnected nature of biology and are constantly evolving as new research is published. These models are available for licensing.

 

     Immunology

 

         Physiology

 

      Critical Care

TH1 cells

TH2 cells

TH17 cells

TH22 cells

B cells

Monocytes

Macrophages

Neutrophils

Eosinophils

Mast cells

Endothelial cells

Epithelial cells

Keratinocytes

Cardiovascular system

Renal system

Pulmonary system

Skin

Joints

Coagulation

Trauma

Inflammation

 


Disease Specific Models

Immunetrics’ disease-specific models span acute inflammation and chronic, autoimmune conditions.

Immunetrics’ disease specific models can be customized to meet specific needs and are constantly evolving to support new research outcomes. These models are available for licensing and for use in consulting projects.


 

 

Disease Models

 

Key Outputs

 

Supported Therapeutics

Rheumatoid Arthritis

Psoriatic Arthritis / Psoriasis

Ulcerative Colitis

Serum cytokines and biomarkers

Serum cell counts

Swollen/tender joint counts

ACR20/50/70

DAS28(3)-CRP/ESR

PASI 50/75/90/100

Mayo score

Response/Remission

MTX

5-ASA

Corticosteroids

JAK inhibitors

Anti-TNFs

Anti-IL6s

Anti-IL17s

Anti-T and B cell therapies

Anti-Survival therapies

Anti-Migration therapies

Sepsis

Multi-Organ Dysfunction

Trauma

Mean arterial pressure (MAP)

Central venous pressure (CVP)

Blood oxygen saturation (O2sat)

Breathing frequency

Tidal volume

Blood gases (PaO2, PaCO2)

Creatinine

Urinary output (UOP)

Coagulation tests (PT, APTT)

Fluid therapy

Vasopressors

Ventilators

Diuretics

Dialysis

Antibiotics