Gary An, M.D., Advisory board member, is a graduate of the University of Miami, Florida School of Medicine, and did his surgical residency at Cook County Hospital/University of Illinois, Chicago. He previously worked as a Trauma Surgeon at Cook County Hospital from 1997 to 2003 and was the Director of the Burn Intensive Care Unit at Cook County Hospital from 2003-2006. He is now a Trauma Surgeon at Northwestern Memorial Hospital in Chicago, IL. He has worked on the application of complex systems analysis to sepsis and inflammation since 1999, using primarily agent based modeling to create mechanistic models of various aspects of the acute inflammatory response. He is a founding member of the Society of Complexity in Acute Illness (SCAI), and is currently that society's Secretary. He has worked closely with the Mathematical Modeling group from the University of Pittsburgh since 2002, where he has been a visiting professor in their graduate-level biomedical modeling course. He is a faculty member of the Center for Inflammation and Regenerative Modeling at the McGowan Institute of Regenerative Medicine at the University of Pittsburgh. He is very active in the agent based modeling community, participating in the Swarm simulation community since 1999. He is the current president of the Swarm Development Group, and was the host of the Group's annual meeting in 2008. He is currently working on the use of agent-based models as a means of dynamic knowledge representation to integrate multiple scales of biological phenomenon. His research involves bioinformatics/ontology development, mechanism-based computer simulation, automated text analysis/information extraction, high-performance/parallel computing architectures for agent-based models and the development of meta-science environments, all with the goal of facilitating transformative scientific research.
Carson Chow, Ph.D., Advisory board member, consultant and co-founder, is an expert in the field of complex systems mathematics and one of the inventors of the Immunetrics technology. Carson is associate professor of mathematics at the University of Pittsburgh, which he joined in 1998. He received his Ph.D. from the Massachusetts Institute of Technology. Carson's research focuses on applied mathematics, with an emphasis on computational biology. In 1999, he was awarded a Sloan Research Fellowship by the Alfred P. Sloan Foundation.
Billy W. Day, Ph.D., Chief Science Consultant, is Associate Professor of Pharmaceutical Sciences, Chemistry and Environmental & Occupational Health at the University of Pittsburgh, as well as founding Director of its Proteomics Facility. He also holds appointments in the Clinical Pharmacology, Molecular Biophysics, Computational Biology & Bioinformatics, Pharmacogenetics, Molecular Pharmacology, Molecular Toxicology, and Computational Toxicology programs at the University of Pittsburgh, and is a member of the University of Pittsburgh Cancer Institute. Billy obtained a double B.S. in Chemistry and Biology from Oklahoma City University and received his Ph.D. in Medicinal Chemistry from the University of Oklahoma. He completed a postdoctoral fellowship at MIT in Chemistry and Toxicology before joining the faculty at the University of Pittsburgh in 1991. Billy serves as consultant to a number of companies including Aventis and Camitro. He is an active member of the American Chemical Society Medicinal Chemistry and Chemical Toxicology sections, including membership on the Editorial Advisory Board for the journal Chemical Research in Toxicology. He is also active in the American Association for Cancer Research Experimental Therapeutics and Molecular Epidemiology sections, including service on the Chemistry in Cancer Research Task Force. Billy has published more than 70 research papers and has given over 120 presentations worldwide. He has also filed a number of patents and has been active in technology development and transfer in the Pittsburgh region. His research has focused on computational drug design, chemical synthesis, pharmacological high-throughput and cell biological high information content screening, and quantitative and qualitative analysis of complex biological mixtures, largely by mass spectrometry.
Steven H. Kleinstein, Ph.D., Advisory board member (www.cs.princeton.edu/~stevenk) is an expert in the field of computational
immunology with over 12 years of experience in computational biology. Steve's research focuses on the development and application of computational methods that leverage mathematical/statistical models and numerical simulations in order to improve understanding of experimental and clinical data. The immune response has been a particular focus of his work. Steve has been associated with several early-stage companies including WorldView Software, Cambridge Technology Group / Object Power, and Physiome Sciences, Inc. (now Predix Pharmaceuticals). At Physiome Sciences, he developed in silico models of disease for large pharmaceutical companies. Steve is currently an Assistant Professor of Pathology at Yale University School of Medicine. He was previously a member of the research staff at Princeton University where he ran the Program in Integrative Information, Computer and Application Sciences (PICASso). He received his Ph.D. in Computer Science from Princeton University in 2002.
Gary An, M.D., Advisory board member, is a graduate of the University of Miami, Florida School of Medicine, and did his surgical residency at Cook County Hospital/University of Illinois, Chicago. He previously worked as a Trauma Surgeon at Cook County Hospital from 1997 to 2003 and was the Director of the Burn Intensive Care Unit at Cook County Hospital from 2003-2006. He is now a Trauma Surgeon at Northwestern Memorial Hospital in Chicago, IL. He has worked on the application of complex systems analysis to sepsis and inflammation since 1999, using primarily agent based modeling to create mechanistic models of various aspects of the acute inflammatory response. He is a founding member of the Society of Complexity in Acute Illness (SCAI), and is currently that society's Secretary. He has worked closely with the Mathematical Modeling group from the University of Pittsburgh since 2002, where he has been a visiting professor in their graduate-level biomedical modeling course. He is a faculty member of the Center for Inflammation and Regenerative Modeling at the McGowan Institute of Regenerative Medicine at the University of Pittsburgh. He is very active in the agent based modeling community, participating in the Swarm simulation community since 1999. He is the current president of the Swarm Development Group, and was the host of the Group's annual meeting in 2008. He is currently working on the use of agent-based models as a means of dynamic knowledge representation to integrate multiple scales of biological phenomenon. His research involves bioinformatics/ontology development, mechanism-based computer simulation, automated text analysis/information extraction, high-performance/parallel computing architectures for agent-based models and the development of meta-science environments, all with the goal of facilitating transformative scientific research.
Carson Chow, Ph.D., Advisory board member, consultant and co-founder, is an expert in the field of complex systems mathematics and one of the inventors of the Immunetrics technology. Carson is associate professor of mathematics at the University of Pittsburgh, which he joined in 1998. He received his Ph.D. from the Massachusetts Institute of Technology. Carson's research focuses on applied mathematics, with an emphasis on computational biology. In 1999, he was awarded a Sloan Research Fellowship by the Alfred P. Sloan Foundation.
Billy W. Day, Ph.D., Chief Science Consultant, is Associate Professor of Pharmaceutical Sciences, Chemistry and Environmental & Occupational Health at the University of Pittsburgh, as well as founding Director of its Proteomics Facility. He also holds appointments in the Clinical Pharmacology, Molecular Biophysics, Computational Biology & Bioinformatics, Pharmacogenetics, Molecular Pharmacology, Molecular Toxicology, and Computational Toxicology programs at the University of Pittsburgh, and is a member of the University of Pittsburgh Cancer Institute. Billy obtained a double B.S. in Chemistry and Biology from Oklahoma City University and received his Ph.D. in Medicinal Chemistry from the University of Oklahoma. He completed a postdoctoral fellowship at MIT in Chemistry and Toxicology before joining the faculty at the University of Pittsburgh in 1991. Billy serves as consultant to a number of companies including Aventis and Camitro. He is an active member of the American Chemical Society Medicinal Chemistry and Chemical Toxicology sections, including membership on the Editorial Advisory Board for the journal Chemical Research in Toxicology. He is also active in the American Association for Cancer Research Experimental Therapeutics and Molecular Epidemiology sections, including service on the Chemistry in Cancer Research Task Force. Billy has published more than 70 research papers and has given over 120 presentations worldwide. He has also filed a number of patents and has been active in technology development and transfer in the Pittsburgh region. His research has focused on computational drug design, chemical synthesis, pharmacological high-throughput and cell biological high information content screening, and quantitative and qualitative analysis of complex biological mixtures, largely by mass spectrometry.
Steven H. Kleinstein, Ph.D., Advisory board member (